The heart needs energy to pump blood. So, energy production defects in heart muscles result in a variety of cardiac diseases.
Texas A&M AgriLife scientists have now discovered a new link between calcium, heart energy production and cardiolipin, a type of fat. The discovery helps explain heart defects in the rare genetic disorder Barth syndrome.
The study, published in Proceedings of the National Academy of Sciences on June 29, was led by Vishal M. Gohil, Ph.D., Department of Biochemistry and Biophysics, Texas A&M College of Agriculture and Life Sciences. Other coauthors were from University of Texas Health Science Center at San Antonio and Massachusetts General Hospital, Boston. The research funding for this study came from the Welch Foundation and the National Institutes of Health.